16748mp4 Apr 2026

You can download the supporting MP4 files directly from the eLife article page under the "Figures and data" section or via PubMed Central.

The paper relies heavily on time-lapse movies to visualize these cellular dynamics. For example, Video 2 (referenced as part of eLife 16748) shows the accumulation and eventual egress of YFP- -catenin in cells treated with Wnt3a. 16748mp4

The team used HEK293 cells and techniques like fluorescence recovery after photobleaching (FRAP) to measure how fast proteins move within the cell. Where to Find the Paper and Videos Full Text (HTML/PDF): Available at eLife Sciences. You can download the supporting MP4 files directly

Published in (2016), this study uses live-cell imaging and mathematical modeling to understand how cells process signals from the Wnt pathway, which is critical for development and often deregulated in cancer. The team used HEK293 cells and techniques like

-catenin subcellular dynamics and cyclin D1 mRNA transcription during Wnt signaling

The researchers tracked the movement of the protein

-catenin levels rise steadily after activation, the actual transcription of the target gene ( CCND1 ) occurs in "bursts" rather than a constant stream.