For many cancer patients, losing hair is a traumatic visible marker of their disease. Scalp cooling works by constricting blood vessels in the scalp. This reduces the amount of chemotherapy drugs reaching the hair follicles. It also decreases the metabolic activity of the follicles, making them less susceptible to damage. Patients generally have two options for scalp cooling:

Cold caps work on a simple physiological principle: vasoconstriction. By lowering the temperature of the scalp right before, during, and after chemotherapy, blood flow to the hair follicles drops by up to 40%. Key findings regarding efficacy include:

Manual caps must maintain a strict temperature (typically around -30°C / -22°F) to be effective. The Financial Reality of "Buying" Cold Caps

Typically costs between $1,500 and $3,000 for a full course of chemotherapy.

Manual capping requires 40 to 50 pounds of dry ice per treatment day, adding hundreds of dollars to the total cost.

Caps must be rotated every 20 to 30 minutes to maintain therapeutic coldness.

Patients often experience headaches, forehead pain, and heavy shivering. Psychological Impact

Treatment requires a dedicated "capper" (friend, family member, or hired professional) to assist.