Hana Yori Dango Episode 21 -

In this version, Episode 21 is a heavy-hitter for the "soulmate" storylines and the lead-up to the finale.

The anime version consists of 51 episodes, and Episode 21 marks a critical turning point in the F4 dynamic. "Night of Betrayal". Hana Yori Dango Episode 21

While on a trip, news breaks that Shizuka (Rui’s first love) is being courted by a French politician and may marry him. Rui is devastated and tells Tsukushi that "it's over". In a moment of vulnerability on the beach, Rui kisses Tsukushi, which is witnessed by Tsukasa (Domyoji). In this version, Episode 21 is a heavy-hitter