The first season of premiered on September 26, 2011, on The CW , introducing viewers to the fish-out-of-water story of Dr. Zoe Hart. The season consists of 22 episodes that blend medical drama with small-town Southern romantic comedy. Core Premise and Storyline

: Zoe learns that Harley Wilkes was actually her biological father. Major Characters and Relationships

Season 1 establishes a complex web of romantic and platonic dynamics: