Mechanism.rar File

RARs act as ligand-activated transcription factors that form heterodimers with Retinoid X Receptors (RXRs) to regulate gene expression.

), encoded by different genes, with distinct tissue-specific expression patterns (e.g., RAR is dominant in skin). Mechanism.rar

Retinoic acid (RA) binds to the RAR-RXR complex within the nucleus, activating it to regulate genes involved in development, differentiation, and apoptosis. Transcriptional Control: RARs act as ligand-activated transcription factors that form