Mydriatic

Mydriatics are pharmacological substances that induce (mydriasis) by stimulating the iris dilator muscle or inhibiting the parasympathetic tone of the iris sphincter muscle. They are foundational tools in modern ophthalmology, essential for comprehensive diagnostic examinations and successful surgical outcomes. 1. Mechanisms of Action

Mydriatic agents generally fall into two categories based on their physiological pathway: mydriatic

These agents, like tropicamide or atropine , block muscarinic receptors on the iris sphincter muscle, preventing its contraction. Many of these also act as cycloplegics , temporarily paralyzing the ciliary muscle to inhibit accommodation. 2. Clinical Applications like tropicamide or atropine

-adrenergic receptors on the iris dilator muscle, causing it to contract and dilate the pupil. and Safety Profiles

Mydriatic Agents: Mechanisms, Clinical Applications, and Safety Profiles