) between an amino acid and a keto acid, playing a key role in amino acid metabolism. : Transfer methyl groups ( −CH3negative cap C cap H sub 3
: Transfer sugar moieties to form glycosidic bonds, which are essential for synthesizing blood group antigens and modifying drug stability.
Transferases are found throughout the cell, with high concentrations in the cytosol, mitochondria, and Golgi bodies. Molecule of the Month: Glutathione Transferases - PDB-101 transferase
Transferases are officially classified under the Enzyme Commission (EC) system as . They follow a general reaction formula:
: Transfer acyl groups, vital for fatty acid metabolism and the synthesis of structured lipids. Biological Roles ) between an amino acid and a keto
A transferase is an enzyme that catalyzes the transfer of a specific functional group (such as a methyl or phosphate group) from a donor molecule to an acceptor molecule. These enzymes are vital for metabolic pathways, including the synthesis and degradation of carbohydrates, proteins, lipids, and nucleic acids. Core Mechanism and Classification
), critical for DNA methylation and gene expression regulation. Molecule of the Month: Glutathione Transferases - PDB-101
: Transfer phosphate groups (typically from ATP) to substrates, a process essential for cell signaling and metabolic regulation. Aminotransferases (EC 2.6) : Transfer amino groups ( −NH2negative cap N cap H sub 2