Allows researchers to concentrate small volumes of protein (e.g., 5 pmol) for more accurate mass determination.
Could you clarify if you need a of a specific study using C4Zip or if you are looking for technical specifications of the product itself?
This research details the use of C4Zip tips to concentrate and desalt purified proteins before elution with a matrix for MALDI-MS analysis. Key Uses of C4Zip Technology:
(2004).
If you are looking for academic papers involving this technology, it is most frequently mentioned in studies concerning protein isolation and characterization. One prominent example is:
Recent developments in mass spectrometry also explore using C4Zip-tip shapes for direct spray ionization from biological samples like human serum.
Efficiently removes salts and buffers from protein samples that could otherwise interfere with mass spectrometry signals.