Titlimp4 -

Recent studies in 2025 demonstrate that .

TIMP4: The Molecular Guardian of Matrix Integrity and Emerging Disease Marker Titlimp4

In patients with idiopathic pulmonary arterial hypertension, a higher plasma MMP2/TIMP4 ratio is used as a predictor of disease severity and worsened survival. 3. Role in Pregnancy and Tissue Remodeling Recent studies in 2025 demonstrate that

Specific genetic variations (C>T polymorphism) in the TIMP4 gene have been associated with a protective effect against preeclampsia in pregnant women. TIMP4 vs. Other TIMPs indicating its anti-inflammatory role in diseases.

Mice lacking the TIMP4 gene showed increased inflammation, indicating its anti-inflammatory role in diseases.